DeNovx was awarded a $224,000 Phase I Small Business Innovative Research grant from the National Institutes of Health to develop new approaches to improve protein crystallization success rates in support of structural biology. The role of structural biology in facilitating an understanding of biological function is well established, and advances in crystallization methods will assist researchers in overcoming crystallization as a major source of attrition in their investigative pipelines.

Improvements in protein crystallization outcomes will positively impact productivity in structural biology, with public health benefits accruing from faster knowledge acquisition and more efficient drug development. The long term objective of this work is to develop consumable products for high throughput screening that will improve protein crystallization success rates for structural biology and drug design.